@article{pmid23529994,

title = {High rates of fructose malabsorption are associated with reduced liver fat in obese African Americans},

author = {R W Walker and K A Lê and J Davis and T L Alderete and R Cherry and S Lebel and M I Goran},

year  = {2012},

date = {2012-01-01},

journal = {J Am Coll Nutr},

volume = {31},

number = {5},

pages = {369--374},

abstract = {African Americans commonly have lower liver fat accumulation than Hispanics, despite a similar propensity for obesity. Both ethnicities exhibit high consumption of fructose-containing beverages, which has been associated with high liver fat owing to the lipogenic properties of fructose. Therefore, differences in fructose absorption may be an important factor in regulating liver fat deposition. We hypothesized that fructose malabsorption in African Americans may reduce hepatic delivery of fructose, thus contributing to lower liver fat deposition compared to Hispanics. Thirty-seven obese young adults aged 21.4 ± 2.1 years (16 African American, 21 Hispanic) underwent a 3-hour hydrogen (H2) breath test to assess fructose malabsorption. Magnetic resonance imaging was used to determine visceral and subcutaneous adipose tissue volume and liver fat. Fructose malabsorption was expressed as an area under the curve for H2 production (H2 AUC). Compared to Hispanics, African Americans had lower liver fat (5.4% ± 5.0% vs 8.9% ± 2.3%},

keywords = {fructose, liver fat},

pubstate = {published},

tppubtype = {article}

}