2012
Davis, J N; Ventura, E E; Tung, A; Munevar, M A; Hasson, R E; Byrd-Williams, C; Vanni, A K; Spruijt-Metz, D; Weigensberg, M; Goran, M I
Effects of a randomized maintenance intervention on adiposity and metabolic risk factors in overweight minority adolescents Journal Article
In: Pediatr Obes, vol. 7, no. 1, pp. 16–27, 2012.
Abstract | BibTeX | Tags: diabetes risk, trial
@article{pmid22434736,
title = {Effects of a randomized maintenance intervention on adiposity and metabolic risk factors in overweight minority adolescents},
author = {J N Davis and E E Ventura and A Tung and M A Munevar and R E Hasson and C Byrd-Williams and A K Vanni and D Spruijt-Metz and M Weigensberg and M I Goran},
year = {2012},
date = {2012-02-01},
journal = {Pediatr Obes},
volume = {7},
number = {1},
pages = {16--27},
abstract = {The objective of this study was to assess the effects of a maintenance programme (monthly newsletters vs. monthly group classes and telephone behavioural sessions) on obesity and metabolic disease risk at 1 year in overweight minority adolescents. After a 4-month nutrition and strength training intervention, 53 overweight Latino and African-American adolescents (15.4 ± 1.1 years) were randomized into one of two maintenance groups for 8 months: monthly newsletters (n = 23) or group classes (n = 30; monthly classes + individualized behavioural telephone sessions). The following outcomes were measured at months 4 (immediately following the intense intervention) and 12: height, weight, blood pressure, body composition via BodPodâ„¢ (Life Measurement Instruments, Concord, CA, USA), lipids and glucose/insulin indices via frequently sampled intravenous glucose tolerance test. There were no significant group by time interactions for any of the health outcomes. There were significant time effects in several outcomes for both groups from months 4 to 12: bench press and leg press decreased by 5% and 14%, respectively (P = 0.004 & P = 0.01), fasting insulin and acute insulin response decreased by 26% and 16%, respectively (P < 0.001 & P = 0.046); while high-density lipoprotein cholesterol and insulin sensitivity improved by 5% and 14% (P = 0.042 & P = 0.039). Newsletters as opposed to group classes may suffice as follow-up maintenance programmes to decrease type 2 diabetes and cardiovascular risk in overweight minority adolescents.},
keywords = {diabetes risk, trial},
pubstate = {published},
tppubtype = {article}
}
The objective of this study was to assess the effects of a maintenance programme (monthly newsletters vs. monthly group classes and telephone behavioural sessions) on obesity and metabolic disease risk at 1 year in overweight minority adolescents. After a 4-month nutrition and strength training intervention, 53 overweight Latino and African-American adolescents (15.4 ± 1.1 years) were randomized into one of two maintenance groups for 8 months: monthly newsletters (n = 23) or group classes (n = 30; monthly classes + individualized behavioural telephone sessions). The following outcomes were measured at months 4 (immediately following the intense intervention) and 12: height, weight, blood pressure, body composition via BodPodâ„¢ (Life Measurement Instruments, Concord, CA, USA), lipids and glucose/insulin indices via frequently sampled intravenous glucose tolerance test. There were no significant group by time interactions for any of the health outcomes. There were significant time effects in several outcomes for both groups from months 4 to 12: bench press and leg press decreased by 5% and 14%, respectively (P = 0.004 & P = 0.01), fasting insulin and acute insulin response decreased by 26% and 16%, respectively (P < 0.001 & P = 0.046); while high-density lipoprotein cholesterol and insulin sensitivity improved by 5% and 14% (P = 0.042 & P = 0.039). Newsletters as opposed to group classes may suffice as follow-up maintenance programmes to decrease type 2 diabetes and cardiovascular risk in overweight minority adolescents.
Hasson, R E; Adam, T C; Davis, J N; Kelly, L A; Ventura, E E; Byrd-Williams, C E; Toledo-Corral, C M; Roberts, C K; Lane, C J; Azen, S P; Chou, C P; Spruijt-Metz, D; Weigensberg, M J; Berhane, K; Goran, M I
Randomized controlled trial to improve adiposity, inflammation, and insulin resistance in obese African-American and Latino youth Journal Article
In: Obesity (Silver Spring), vol. 20, no. 4, pp. 811–818, 2012.
Abstract | BibTeX | Tags: diabetes risk, trial
@article{pmid21293446,
title = {Randomized controlled trial to improve adiposity, inflammation, and insulin resistance in obese African-American and Latino youth},
author = {R E Hasson and T C Adam and J N Davis and L A Kelly and E E Ventura and C E Byrd-Williams and C M Toledo-Corral and C K Roberts and C J Lane and S P Azen and C P Chou and D Spruijt-Metz and M J Weigensberg and K Berhane and M I Goran},
year = {2012},
date = {2012-00-01},
journal = {Obesity (Silver Spring)},
volume = {20},
number = {4},
pages = {811--818},
abstract = {The purpose of this study was to examine ethnic differences in the metabolic responses to a 16-week intervention designed to improve insulin sensitivity (SI), adiposity, and inflammation in obese African-American and Latino adolescents. A total of 100 participants (African Americans: n = 48, Latino: n = 52; age: 15.4 ± 1.1 years, BMI percentile: 97.3 ± 3.3) were randomly assigned to interventions: control (C; n = 30), nutrition (N; n = 39, 1×/week focused on decreasing sugar and increasing fiber intake), or nutrition + strength training (N+ST; n = 31, 2×/week). The following were measured at pre- and postintervention: strength, dietary intake, body composition (dual-energy X-ray absorptiometry/magnetic resonance imaging) and glucose/insulin indexes (oral glucose tolerance test (OGTT)/intravenous glucose tolerance test (IVGTT)) and inflammatory markers. Overall, N compared to C and N+ST reported significant improvements in SI (+16.5% vs. -32.3% vs. -6.9% respectively, P < 0.01) and disposition index (DI: +15.5% vs. -14.2% vs. -13.7% respectively, P < 0.01). N+ST compared to C and N reported significant reductions in hepatic fat fraction (HFF: -27.3% vs. -4.3% vs. 0% respectively, P < 0.01). Compared to N, N+ST reported reductions in plasminogen activator inhibitor-1 (PAI-1) (-38.3% vs. +1.0%, P < 0.01) and resistin (-18.7% vs. +11.3%},
keywords = {diabetes risk, trial},
pubstate = {published},
tppubtype = {article}
}
The purpose of this study was to examine ethnic differences in the metabolic responses to a 16-week intervention designed to improve insulin sensitivity (SI), adiposity, and inflammation in obese African-American and Latino adolescents. A total of 100 participants (African Americans: n = 48, Latino: n = 52; age: 15.4 ± 1.1 years, BMI percentile: 97.3 ± 3.3) were randomly assigned to interventions: control (C; n = 30), nutrition (N; n = 39, 1×/week focused on decreasing sugar and increasing fiber intake), or nutrition + strength training (N+ST; n = 31, 2×/week). The following were measured at pre- and postintervention: strength, dietary intake, body composition (dual-energy X-ray absorptiometry/magnetic resonance imaging) and glucose/insulin indexes (oral glucose tolerance test (OGTT)/intravenous glucose tolerance test (IVGTT)) and inflammatory markers. Overall, N compared to C and N+ST reported significant improvements in SI (+16.5% vs. -32.3% vs. -6.9% respectively, P < 0.01) and disposition index (DI: +15.5% vs. -14.2% vs. -13.7% respectively, P < 0.01). N+ST compared to C and N reported significant reductions in hepatic fat fraction (HFF: -27.3% vs. -4.3% vs. 0% respectively, P < 0.01). Compared to N, N+ST reported reductions in plasminogen activator inhibitor-1 (PAI-1) (-38.3% vs. +1.0%, P < 0.01) and resistin (-18.7% vs. +11.3%
2011
Ball, G D; Mackenzie-Rife, K A; Newton, M S; Alloway, C A; Slack, J M; Plotnikoff, R C; Goran, M I
One-on-one lifestyle coaching for managing adolescent obesity: Findings from a pilot, randomized controlled trial in a real-world, clinical setting Journal Article
In: Paediatr Child Health, vol. 16, no. 6, pp. 345–350, 2011.
Abstract | BibTeX | Tags: pediatric obesity, trial
@article{pmid22654546,
title = {One-on-one lifestyle coaching for managing adolescent obesity: Findings from a pilot, randomized controlled trial in a real-world, clinical setting},
author = {G D Ball and K A Mackenzie-Rife and M S Newton and C A Alloway and J M Slack and R C Plotnikoff and M I Goran},
year = {2011},
date = {2011-06-01},
journal = {Paediatr Child Health},
volume = {16},
number = {6},
pages = {345--350},
abstract = {Interventions for obese adolescents in real-world, clinical settings need to be evaluated because most weight management care occurs in this context. To determine whether a lifestyle intervention that includes motivational interviewing and cognitive behavioural therapy (Health Initiatives Program [HIP]) leads to weight management that is superior to a similar lifestyle intervention (Youth Lifestyle Program [YLP]) that does not include these techniques; and to determine whether the HIP and YLP interventions are superior to a wait list control (WLC) group. Obese adolescents were randomly assigned to a YLP (n=15), HIP (n=17) or WLC (n=14) group. The YLP and HIP were 16-session, one-on-one interventions. The primary outcome was the percentage change of body mass index z-score. Completers-only analyses revealed 3.9% (YLP) and 6.5% (HIP) decreases in the percentage change of body mass index z-score compared with a 0.8% (WLC) increase (P<0.001). Levels of attrition did not differ among groups, but were relatively high (approximately 20% to 40%). Lifestyle interventions delivered in a real-world, clinical setting led to short-term improvements in the obesity status of adolescents.},
keywords = {pediatric obesity, trial},
pubstate = {published},
tppubtype = {article}
}
Interventions for obese adolescents in real-world, clinical settings need to be evaluated because most weight management care occurs in this context. To determine whether a lifestyle intervention that includes motivational interviewing and cognitive behavioural therapy (Health Initiatives Program [HIP]) leads to weight management that is superior to a similar lifestyle intervention (Youth Lifestyle Program [YLP]) that does not include these techniques; and to determine whether the HIP and YLP interventions are superior to a wait list control (WLC) group. Obese adolescents were randomly assigned to a YLP (n=15), HIP (n=17) or WLC (n=14) group. The YLP and HIP were 16-session, one-on-one interventions. The primary outcome was the percentage change of body mass index z-score. Completers-only analyses revealed 3.9% (YLP) and 6.5% (HIP) decreases in the percentage change of body mass index z-score compared with a 0.8% (WLC) increase (P<0.001). Levels of attrition did not differ among groups, but were relatively high (approximately 20% to 40%). Lifestyle interventions delivered in a real-world, clinical setting led to short-term improvements in the obesity status of adolescents.